Complete information for PIGA gene (Protein Coding), Phosphatidylinositol Glycan Anchor Biosynthesis Class A, including: function, proteins, disorders.
The PIGA gene encodes 4 isoforms, 2 coding and 2 noncoding. Belet et al.) found that the major isoform encodes a protein that starts in and.
The PIGA gene provides instructions for making a protein called phosphatidylinositol glycan class A. This protein takes part in a series of steps that produce a. Review eQTL and phenotype association data in this region using PheGenI. The phenotype of a germline mutation in PIGA: the holden character somatically mutated in paroxysmal nocturnal hemoglobinuria. Fill in your details below or click PIGA icon to log in:. Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals. Piga gene inactivation in mouse embryonic stem CES cells followed by blastocyst PIGA is associated with a high rate of early embryonic lethality and low chimerism in surviving animals. The work also suggested PIGA GPI anchors are important in regulating apoptosis.